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Intrathecal trastuzumab for leptomeningeal carcinomatosis in patients with human epidermal growth factor receptor 2 positive breast cancer

There has been recent increase in incidence of leptomeningeal carcinomatosis, possibly due to widespread use of adjuvant trastuzumab and its known poor CNS penetration. Currently there are limited therapeutic options for these patients and outcome is poor. We report two cases of women with HER2 posi...

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Detalhes bibliográficos
Publicado no:Indian J Med Paediatr Oncol
Main Authors: Gulia, Seema, Gupta, Sudeep, Singh, Ashish
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027793/
https://ncbi.nlm.nih.gov/pubmed/27688614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5851.190354
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