EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI

Enhancer of zeste homolog 2 (EZH2) trimethylates histone H3 Lys 27 and plays key roles in a variety of biological processes. Stability of spindle assembly checkpoint protein BubR1 is essential for mitosis in somatic cells and for meiosis in oocytes. However, the role of EZH2 in oocyte meiotic matura...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Qu, Yi, Lu, Danyu, Jiang, Hao, Chi, Xiaochun, Zhang, Hongquan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027481/
https://ncbi.nlm.nih.gov/pubmed/27226494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw463
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