Ultra-sensitive detection of brain-derived neurotrophic factor (BDNF) in the brain of freely moving mice using an interdigitated microelectrode (IME) biosensor

Brain-derived neurotrophic factor (BDNF) plays a critical role in cognitive processes including learning and memory. However, it has been difficult to detect BDNF in the brains of behaving animals because of its extremely low concentration, i.e., at the sub-nanogram/mL level. Here, we developed an i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yoo, Yong Kyoung, Lee, Jaekwang, Kim, Jinsik, Kim, Gangeun, Kim, Sunpil, Kim, Jeongyeon, Chun, Heejung, Lee, Jeong Hoon, Lee, C. Justin, Hwang, Kyo Seon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027392/
https://ncbi.nlm.nih.gov/pubmed/27640722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33694
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