Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways

Obstructive sleep apnea (OSA) associated chronic kidney disease is mainly caused by chronic intermittent hypoxia (CIH) triggered tissue damage. Receptor for advanced glycation end product (RAGE) and its ligand high mobility group box 1 (HMGB1) are expressed on renal cells and mediate inflammatory re...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wu, Xu, Gu, Wenyu, Lu, Huan, Liu, Chengying, Yu, Biyun, Xu, Hui, Tang, Yaodong, Li, Shanqun, Zhou, Jian, Shao, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027322/
https://ncbi.nlm.nih.gov/pubmed/27688824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1015390
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