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Nrf2 modulates host defense during S. pneumoniae pneumonia in mice

Nrf2 regulates the transcriptional response to oxidative stress. These studies tested the role of Nrf2 during S. pneumoniae pneumonia and identified Nrf2-dependent genes and pathways in lung tissue and in recruited neutrophils. Nrf2 null and WT mice were studied at 6 and 24 h following instillation...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Gomez, John C., Dang, Hong, Martin, Jessica R., Doerschuk, Claire M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026972/
https://ncbi.nlm.nih.gov/pubmed/27566827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600043
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