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Kinetic partitioning during de novo septin filament assembly creates a critical G1 “window of opportunity” for mutant septin function
Septin proteins form highly conserved cytoskeletal filaments composed of hetero-oligomers with strict subunit stoichiometry. Mutations within one hetero-oligomerization interface (the “G” interface) bias the mutant septin toward conformations that are incompatible with filament assembly, causing dis...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026808/ https://ncbi.nlm.nih.gov/pubmed/27398993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1196304 |
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