Cancer associated fibroblasts in pancreatic cancer are reprogrammed by tumor-induced alterations in genomic DNA methylation

Stromal fibrosis is a prominent histological characteristic of pancreatic ductal adenocarcinoma (PDAC), but how stromal fibroblasts are regulated in the tumor microenvironment (TME) to support tumor growth is largely unknown. Here we show that PDAC cells can induce DNA methylation in cancer associat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: Xiao, Qian, Zhou, Donger, Rucki, Agnieszka A., Williams, Jamila, Zhou, Jiaojiao, Mo, Guanglan, Murphy, Adrian, Fujiwara, Kenji, Kleponis, Jennifer, Salman, Bulent, Wolfgang, Christopher L., Anders, Robert A., Zheng, Shu, Jaffee, Elizabeth M., Zheng, Lei
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026619/
https://ncbi.nlm.nih.gov/pubmed/27496707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3264
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars