Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia

Somatic genetic abnormalities are initiators and drivers of disease and have proven clinical utility at initial diagnosis. However, the genetic landscape and its clinical utility at relapse are less well understood and have not been studied comprehensively. We analyzed cytogenetic data from 427 chil...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Irving, Julie A. E., Enshaei, Amir, Parker, Catriona A., Sutton, Rosemary, Kuiper, Roland P., Erhorn, Amy, Minto, Lynne, Venn, Nicola C., Law, Tamara, Yu, Jiangyan, Schwab, Claire, Davies, Rosanna, Matheson, Elizabeth, Davies, Alysia, Sonneveld, Edwin, den Boer, Monique L., Love, Sharon B., Harrison, Christine J., Hoogerbrugge, Peter M., Revesz, Tamas, Saha, Vaskar, Moorman, Anthony V.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026463/
https://ncbi.nlm.nih.gov/pubmed/27229005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-704973
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