Nitrodibenzofuran: A One- and Two-Photon Sensitive Protecting Group That Is Superior to Brominated Hydroxycoumarin for Thiol Caging in Peptides

[Image: see text] Photoremovable protecting groups are important for a wide range of applications in peptide chemistry. Using Fmoc-Cys(Bhc-MOM)-OH, peptides containing a Bhc-protected cysteine residue can be easily prepared. However, such protected thiols can undergo isomerization to a dead-end prod...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Mahmoodi, M. Mohsen, Abate-Pella, Daniel, Pundsack, Tom J., Palsuledesai, Charuta C., Goff, Philip C., Blank, David A., Distefano, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026405/
https://ncbi.nlm.nih.gov/pubmed/27027927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b11759
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