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Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data

BACKGROUND: Tissue Angiotensin II (Ang-II), produced through local non ACE-dependent pathways, stimulates liver fibrogenesis, renal vasoconstriction and sodium retention. AIM: To highlight chymase-dependent pathway of Ang-II production in liver and kidney during cirrhosis development. METHODS: Liver...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Sansoè, Giovanni, Aragno, Manuela, Mastrocola, Raffaella, Mengozzi, Giulio, Novo, Erica, Parola, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026361/
https://ncbi.nlm.nih.gov/pubmed/27637026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162644
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