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SMCis: An Effective Algorithm for Discovery of Cis-Regulatory Modules

The discovery of cis-regulatory modules (CRMs) is a challenging problem in computational biology. Limited by the difficulty of using an HMM to model dependent features in transcriptional regulatory sequences (TRSs), the probabilistic modeling methods based on HMMs cannot accurately represent the dis...

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Pubblicato in:PLoS One
Autori principali: Guo, Haitao, Huo, Hongwei, Yu, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026350/
https://ncbi.nlm.nih.gov/pubmed/27637070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162968
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