Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically Encoded pH Sensors

Astrocytes can both sense and shape the evolution of neuronal network activity and are known to possess unique ion regulatory mechanisms. Here we explore the relationship between astrocytic intracellular pH dynamics and the synchronous network activity that occurs during seizure-like activity. By co...

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Udgivet i:J Neurosci
Main Authors: Raimondo, Joseph V., Tomes, Hayley, Irkle, Agnese, Kay, Louise, Kellaway, Lauriston, Markram, Henry, Millar, Robert P., Akerman, Colin J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026294/
https://ncbi.nlm.nih.gov/pubmed/27358457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0664-16.2016
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