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The potential of venetoclax (ABT-199) in chronic lymphocytic leukemia
Venetoclax (VEN, ABT-199/GDC-0199) is an orally bioavailable BH3-mimetic that specifically inhibits the anti-apoptotic B-cell lymphoma/leukemia 2 (BCL2) protein. Although BCL2 overexpression is not genetically driven in chronic lymphocytic leukemia (CLL), it is nearly universal and represents a high...
Gardado en:
| Publicado en: | Ther Adv Hematol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SAGE Publications
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026291/ https://ncbi.nlm.nih.gov/pubmed/27695617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620716655350 |
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