Presence of Macrophages and Inflammatory Responses in an In Vitro Testicular Co-Culture Model of Male Reproductive Development Enhance Relevance to In Vivo Conditions

Our 3-dimensional testis co-culture system (3D-TCS) represents a promising model of male reproductive toxicity which captures sensitive processes of male reproductive development and contains the main testes cell types (germ, Leydig and Sertoli cells). Macrophages are another cell type important for...

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Veröffentlicht in:Toxicol In Vitro
Hauptverfasser: Harris, Sean, Shubin, Sara Pacheco, Wegner, Susanna, Van Ness, Kirk, Green, Foad, Hong, Sung Woo, Faustman, Elaine M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026229/
https://ncbi.nlm.nih.gov/pubmed/27511800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2016.08.003
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