Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds

The pal/RIM ambient pH signalling pathway is crucial for the ability of pathogenic fungi to infect hosts. The Aspergillus nidulans 7‐TMD receptor PalH senses alkaline pH, subsequently facilitating ubiquitination of the arrestin PalF. Ubiquitinated PalF triggers downstream signalling events. The mech...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Microbiol
Prif Awduron: Lucena‐Agell, Daniel, Hervás‐Aguilar, América, Múnera‐Huertas, Tatiana, Pougovkina, Olga, Rudnicka, Joanna, Galindo, Antonio, Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026065/
https://ncbi.nlm.nih.gov/pubmed/27279148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13438
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