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Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds
The pal/RIM ambient pH signalling pathway is crucial for the ability of pathogenic fungi to infect hosts. The Aspergillus nidulans 7‐TMD receptor PalH senses alkaline pH, subsequently facilitating ubiquitination of the arrestin PalF. Ubiquitinated PalF triggers downstream signalling events. The mech...
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| 出版年: | Mol Microbiol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026065/ https://ncbi.nlm.nih.gov/pubmed/27279148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13438 |
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