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Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds

The pal/RIM ambient pH signalling pathway is crucial for the ability of pathogenic fungi to infect hosts. The Aspergillus nidulans 7‐TMD receptor PalH senses alkaline pH, subsequently facilitating ubiquitination of the arrestin PalF. Ubiquitinated PalF triggers downstream signalling events. The mech...

詳細記述

保存先:
書誌詳細
出版年:Mol Microbiol
主要な著者: Lucena‐Agell, Daniel, Hervás‐Aguilar, América, Múnera‐Huertas, Tatiana, Pougovkina, Olga, Rudnicka, Joanna, Galindo, Antonio, Tilburn, Joan, Arst, Herbert N., Peñalva, Miguel A.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026065/
https://ncbi.nlm.nih.gov/pubmed/27279148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13438
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