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Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Neuronal epigenomes, including chromosomal loopings moving distal cis-regulatory elements into proximity of target genes, could serve as molecular proxy linking present-day-behaviour to past exposures. However, longitudinal assessment of chromatin state is challenging, because conventional chromosom...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Mitchell, Amanda C., Javidfar, Behnam, Bicks, Lucy K., Neve, Rachael, Garbett, Krassimira, Lander, Sharon S., Mirnics, Karoly, Morishita, Hirofumi, Wood, Marcelo A., Jiang, Yan, Gaisler-Salomon, Inna, Akbarian, Schahram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025847/
https://ncbi.nlm.nih.gov/pubmed/27597321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12743
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