Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

Bacterial resistance against classical antibiotics is a growing problem and the development of new antibiotics is limited. Thus, novel alternatives to antibiotics are warranted. Antimicrobial peptides (AMPs) are effector molecules of innate immunity that can be induced by several compounds, includin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miraglia, Erica, Nylén, Frank, Johansson, Katarina, Arnér, Elias, Cebula, Marcus, Farmand, Susan, Ottosson, Håkan, Strömberg, Roger, Gudmundsson, Gudmundur H., Agerberth, Birgitta, Bergman, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025742/
https://ncbi.nlm.nih.gov/pubmed/27633343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33274
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