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The N-terminal domain plays a crucial role in the structure of a full-length human mitochondrial Lon protease
Lon is an essential, multitasking AAA(+) protease regulating many cellular processes in species across all kingdoms of life. Altered expression levels of the human mitochondrial Lon protease (hLon) are linked to serious diseases including myopathies, paraplegia, and cancer. Here, we present the firs...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025710/ https://ncbi.nlm.nih.gov/pubmed/27632940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33631 |
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