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HIV-1 Tat-shortened neurite outgrowth through regulation of microRNA-132 and its target gene expression
BACKGROUND: Synaptodendritic damage is a pathological hallmark of HIV-associated neurocognitive disorders, and HIV-1 Tat protein is known to cause such injury in the central nervous system. In this study, we aimed to determine the molecular mechanisms of Tat-induced neurite shortening, specifically...
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Publicado no: | J Neuroinflammation |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025601/ https://ncbi.nlm.nih.gov/pubmed/27634380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0716-2 |
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