RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis.
The N-terminal nucleotide binding folds of all 10 class I tRNA synthetases (RSs) contain characteristic conserved sequence motifs that define this class of synthetases. Sequences of C-terminal domains, which in some cases are known to interact with anticodons, are divergent. In the 676-amino acid Es...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9964 |
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