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Hepatitis C Virus Selectively Alters the Intracellular Localization of Desmosterol
Hepatitis C virus (HCV) increases intracellular desmosterol without affecting the steady-state abundance of other sterols, and the antiviral activity of inhibitors of desmosterol synthesis is suppressed by the addition of exogenous desmosterol. These observations suggest a model in which desmosterol...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025300/ https://ncbi.nlm.nih.gov/pubmed/27128812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00324 |
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