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Sir protein–independent repair of dicentric chromosomes in Saccharomyces cerevisiae

Sir2 protein has been reported to be recruited to dicentric chromosomes under tension, and such chromosomes are reported to be especially vulnerable to breakage in sir2Δ mutants. We found that the loss of viability in such mutants was an indirect effect of the repression of nonhomologous end joining...

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Vydáno v:Mol Biol Cell
Hlavní autoři: McCleary, David F., Steakley, David Lee, Rine, Jasper
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025274/
https://ncbi.nlm.nih.gov/pubmed/27466318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0102
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