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Sir protein–independent repair of dicentric chromosomes in Saccharomyces cerevisiae

Sir2 protein has been reported to be recruited to dicentric chromosomes under tension, and such chromosomes are reported to be especially vulnerable to breakage in sir2Δ mutants. We found that the loss of viability in such mutants was an indirect effect of the repression of nonhomologous end joining...

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Publicado en:Mol Biol Cell
Main Authors: McCleary, David F., Steakley, David Lee, Rine, Jasper
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025274/
https://ncbi.nlm.nih.gov/pubmed/27466318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0102
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