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Coenzyme Q10 plus Multivitamin Treatment Prevents Cisplatin Ototoxicity in Rats

Cisplatin (Cpt) is known to induce a high level of oxidative stress, resulting in an increase of reactive oxygen species damaging the inner ear and causing hearing loss at high frequencies. Studies on animal models show that antioxidants may lower Cpt-induced ototoxicity. The aim of this study is to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Astolfi, Laura, Simoni, Edi, Valente, Filippo, Ghiselli, Sara, Hatzopoulos, Stavros, Chicca, Milvia, Martini, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025172/
https://ncbi.nlm.nih.gov/pubmed/27632426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162106
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