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Small GSK-3 Inhibitor Shows Efficacy in a Motor Neuron Disease Murine Model Modulating Autophagy

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that has no effective treatment up to date. Drug discovery tasks have been hampered due to the lack of knowledge in its molecular etiology together with the limited animal models for research. Recently, a motor ne...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: de Munck, Estefanía, Palomo, Valle, Muñoz-Sáez, Emma, Perez, Daniel I., Gómez-Miguel, Begoña, Solas, M. Teresa, Gil, Carmen, Martínez, Ana, Arahuetes, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025054/
https://ncbi.nlm.nih.gov/pubmed/27631495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162723
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