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FliW antagonizes CsrA RNA binding by a noncompetitive allosteric mechanism

CsrA (carbon storage regulator A) is a widely distributed bacterial RNA binding protein that regulates translation initiation and mRNA stability of target transcripts. In γ-proteobacteria, CsrA activity is competitively antagonized by one or more small RNAs (sRNAs) containing multiple CsrA binding s...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mukherjee, Sampriti, Oshiro, Reid T., Yakhnin, Helen, Babitzke, Paul, Kearns, Daniel B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024615/
https://ncbi.nlm.nih.gov/pubmed/27516547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602455113
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