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Evolved plasmid-host interactions reduce plasmid interference cost

Antibiotic selection drives adaptation of antibiotic resistance plasmids to new bacterial hosts, but the molecular mechanisms are still poorly understood. We previously showed that a broad-host-range plasmid was poorly maintained in Shewanella oneidensis, but rapidly adapted through mutations in the...

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Bibliographic Details
Published in:Mol Microbiol
Main Authors: Yano, Hirokazu, Wegrzyn, Katarznya, Loftie-Eaton, Wesley, Johnson, Jenny, Deckert, Gail E., Rogers, Linda M., Konieczny, Igor, Top, Eva M.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024541/
https://ncbi.nlm.nih.gov/pubmed/27121483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13407
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