Urate crystal deposition and bone erosion in gout: ‘inside-out’ or ‘outside-in’? A dual-energy computed tomography study

BACKGROUND: It is currently unknown whether bone erosion in gout occurs through an ‘inside-out’ mechanism due to direct intra-osseous crystal deposition or through an ‘outside-in’ mechanism from the surface of bone. The aim of this study was to examine the mechanism (‘outside-in’ vs. ‘inside-out’) o...

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Udgivet i:Arthritis Res Ther
Main Authors: Towiwat, Patapong, Doyle, Anthony J., Gamble, Gregory D., Tan, Paul, Aati, Opetaia, Horne, Anne, Stamp, Lisa K., Dalbeth, Nicola
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024428/
https://ncbi.nlm.nih.gov/pubmed/27629724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1105-z
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