HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome

In cervical squamous cell carcinomas, high-risk human papillomavirus (HRHPV) DNA is usually integrated into host chromosomes. Multiple integration events are thought to be present within the cells of a polyclonal premalignant lesion and the features that underpin clonal selection of one particular i...

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Detalles Bibliográficos
Publicado en:Oncogene
Autores principales: Groves, I J, Knight, E L A, Ang, Q Y, Scarpini, C G, Coleman, N
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024154/
https://ncbi.nlm.nih.gov/pubmed/26876196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.8
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