Correlation of Low CD73 Expression on Synovial Lymphocytes With Reduced Adenosine Generation and Higher Disease Severity in Juvenile Idiopathic Arthritis

OBJECTIVE: To investigate the expression and adenosine‐generating activity of the ecto‐5′‐nucleotidase CD73 on synovial fluid mononuclear cells (SFMCs) and peripheral blood mononuclear cells (PBMCs) from children with juvenile idiopathic arthritis (JIA). METHODS: Given the role of CD73 protein in th...

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Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: Botta Gordon‐Smith, Sophie, Ursu, Simona, Eaton, Simon, Moncrieffe, Halima, Wedderburn, Lucy R.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Pediatric Rheumatology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024010/
https://ncbi.nlm.nih.gov/pubmed/25418634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38959
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