Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning

Type 2 diabetes mellitus is associated with accelerated cognitive decline. The underlying pathophysiological mechanisms still remain to be elucidated although it is known that insulin signaling modulates neurotransmitter activity, including inhibitory γ-aminobutyric acid (GABA) and excitatory glutam...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: van Bussel, Frank C.G., Backes, Walter H., Hofman, Paul A.M., Puts, Nicolaas A.J., Edden, Richard A.E., van Boxtel, Martin P.J., Schram, Miranda T., Stehouwer, Coen D.A., Wildberger, Joachim E., Jansen, Jacobus F.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2016
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4300
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023915/
https://ncbi.nlm.nih.gov/pubmed/27603392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000004803
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