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An investigation of the association of genetic susceptibility risk with somatic mutation burden in breast cancer

BACKGROUND: Genome-wide association studies have reported nearly 100 common germline susceptibility loci associated with the risk for breast cancer. Tumour sequencing studies have characterised somatic mutation profiles in breast cancer patients. The relationship between breast cancer susceptibility...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Zhu, Bin, Mukherjee, Anwesha, Machiela, Mitchell J, Song, Lei, Hua, Xing, Shi, Jianxin, Garcia-Closas, Montserrat, Chanock, Stephen J, Chatterjee, Nilanjan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023771/
https://ncbi.nlm.nih.gov/pubmed/27467053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.223
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