Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic patients. However, PLT transfusion refractoriness is a common life-threatening condition observed in multitransfused patients. The most frequent immune cause for PLT transfusion refractoriness is the presence of...

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Pubblicato in:Mol Med
Autori principali: Börger, Ann-Kathrin, Eicke, Dorothee, Wolf, Christina, Gras, Christiane, Aufderbeck, Susanne, Schulze, Kai, Engels, Lena, Eiz-Vesper, Britta, Schambach, Axel, Guzman, Carlos A, Lachmann, Nico, Moritz, Thomas, Martin, Ulrich, Blasczyk, Rainer, Figueiredo, Constança
Natura: Artigo
Lingua:Inglês
Pubblicazione: Feinstein Institute for Medical Research 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023513/
https://ncbi.nlm.nih.gov/pubmed/27262025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00235
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