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α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells
Pluripotent stem cells (PSCs) can self-renew or differentiate from naïve or more differentiated, primed, pluripotent states established by specific culture conditions. Increased intracellular α-ketoglutarate (αKG) was shown to favor self-renewal in naïve mouse embryonic stem cells (mESCs). The effec...
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| Опубликовано в: : | Cell Metab |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023506/ https://ncbi.nlm.nih.gov/pubmed/27476976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.07.002 |
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