Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate

Benzyl isothiocyanate (BITC) is a highly promising phytochemical abundant in cruciferous vegetables with preclinical evidence of in vivo efficacy against breast cancer in xenograft and transgenic mouse models. Mammary cancer chemoprevention by BITC is associated with apoptotic cell death but the und...

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Veröffentlicht in:Mitochondrion
Hauptverfasser: Sehrawat, Anuradha, St. Croix, Claudette, Baty, Catherine J., Watkins, Simon, Tailor, Dhanir, Singh, Rana P., Singh, Shivendra V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023488/
https://ncbi.nlm.nih.gov/pubmed/27374852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2016.06.006
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