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Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior

RATIONALE: Contemporary animal models of cocaine addiction focus on increasing the amount of drug consumption to produce addiction-like behavior. However, another critical factor is the temporal pattern of consumption, which in humans is characterized by intermittency, both within and between bouts...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Kawa, Alex B., Bentzley, Brandon S., Robinson, Terry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023484/
https://ncbi.nlm.nih.gov/pubmed/27481050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4393-8
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