Cumulative tenofovir disoproxil fumarate exposure is associated with biomarkers of tubular injury and fibrosis in HIV-infected men

Tenofovir disoproxil fumarate (TDF) can cause kidney damage, but current clinical tests are insensitive for detecting toxicity. Among 884 HIV-infected men enrolled in the Multicenter AIDS Cohort Study, we measured urine biomarkers specific for tubular damage (interleukin-18 (IL-18), kidney injury mo...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Jotwani, Vasantha, Scherzer, Rebecca, Estrella, Michelle M., Jacobson, Lisa P., Witt, Mallory D., Palella, Frank, Macatangay, Bernard, Bennett, Michael, Parikh, Chirag R, Ix, Joachim H, Shlipak, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023456/
https://ncbi.nlm.nih.gov/pubmed/27088295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001027
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