(18)F-FDG PET/CT for Monitoring the Response of Breast Cancer to miR-143-Based Therapeutics by Targeting Tumor Glycolysis

Increased glucose utilization is a hallmark of cancer, and tumor metabolism is emerging as anticancer target for therapeutic intervention. Triple-negative breast cancers TNBC are highly glycolytic and show poor clinical outcomes. We previously identified hexokinase 2, the major glycolytic enzyme, as...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Miao, Ying, Zhang, Ling-fei, Guo, Rui, Liang, Sheng, Zhang, Min, Shi, Shuo, Shang-Guan, Cheng-fang, Liu, Mo-fang, Li, Biao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023410/
https://ncbi.nlm.nih.gov/pubmed/27574783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.72
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