Vastatin, an Endogenous Antiangiogenesis Polypeptide That Is Lost in Hepatocellular Carcinoma, Effectively Inhibits Tumor Metastasis

Hepatocellular carcinoma (HCC) is a hypervascular cancer without effective treatment. Here we report that polypeptide of NC1 domain of type VIII collagen (Vastatin) is an endogenous polypeptide expressed in normal liver tissue but lost in the liver of most HCC patients (73.1%). Its expression level...

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Bibliografiska uppgifter
I publikationen:Mol Ther
Huvudupphovsmän: Shen, Zan, Yao, Chen, Wang, Zifeng, Yue, Lu, Fang, Zheping, Yao, Hong, Lin, Feng, Zhao, Hui, Sun, Yuan-Jue, Bian, Xiu-wu, Jiang, Wenqi, Wang, Xiaomei, Li, Yi, Lu, Gang, Poon, Wai Sang, Kung, Hsiang-Fu, Lin, Marie Chia-mi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023388/
https://ncbi.nlm.nih.gov/pubmed/26961408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.56
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