Vastatin, an Endogenous Antiangiogenesis Polypeptide That Is Lost in Hepatocellular Carcinoma, Effectively Inhibits Tumor Metastasis

Hepatocellular carcinoma (HCC) is a hypervascular cancer without effective treatment. Here we report that polypeptide of NC1 domain of type VIII collagen (Vastatin) is an endogenous polypeptide expressed in normal liver tissue but lost in the liver of most HCC patients (73.1%). Its expression level...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Shen, Zan, Yao, Chen, Wang, Zifeng, Yue, Lu, Fang, Zheping, Yao, Hong, Lin, Feng, Zhao, Hui, Sun, Yuan-Jue, Bian, Xiu-wu, Jiang, Wenqi, Wang, Xiaomei, Li, Yi, Lu, Gang, Poon, Wai Sang, Kung, Hsiang-Fu, Lin, Marie Chia-mi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023388/
https://ncbi.nlm.nih.gov/pubmed/26961408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.56
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