Vastatin, an Endogenous Antiangiogenesis Polypeptide That Is Lost in Hepatocellular Carcinoma, Effectively Inhibits Tumor Metastasis

Hepatocellular carcinoma (HCC) is a hypervascular cancer without effective treatment. Here we report that polypeptide of NC1 domain of type VIII collagen (Vastatin) is an endogenous polypeptide expressed in normal liver tissue but lost in the liver of most HCC patients (73.1%). Its expression level...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Shen, Zan, Yao, Chen, Wang, Zifeng, Yue, Lu, Fang, Zheping, Yao, Hong, Lin, Feng, Zhao, Hui, Sun, Yuan-Jue, Bian, Xiu-wu, Jiang, Wenqi, Wang, Xiaomei, Li, Yi, Lu, Gang, Poon, Wai Sang, Kung, Hsiang-Fu, Lin, Marie Chia-mi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023388/
https://ncbi.nlm.nih.gov/pubmed/26961408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.56
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