Adenoviral Delivery of Tumor Necrosis Factor-α and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma

Adoptive T-cell transfer is a promising treatment approach for metastatic cancer, but efficacy in solid tumors has only been achieved with toxic pre- and postconditioning regimens. Thus, adoptive T-cell therapies would benefit from complementary modalities that enable their full potential without ex...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Siurala, Mikko, Havunen, Riikka, Saha, Dipongkor, Lumen, Dave, Airaksinen, Anu J., Tähtinen, Siri, Cervera-Carrascon, Víctor, Bramante, Simona, Parviainen, Suvi, Vähä-Koskela, Markus, Kanerva, Anna, Hemminki, Akseli
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023385/
https://ncbi.nlm.nih.gov/pubmed/27357626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.137
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