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Methylation of DNA in megaloblastic anaemia.

Methylation of cytosine residues in DNA samples, collected before and serially after cobalamin treatment from patients with cobalamin deficiency, was studied using restriction endonucleases Hpa II and Msp I and an epsilon globin gene probe. There was no evidence of hypomethylation in any of the samp...

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Bibliographic Details
Published in:J Clin Pathol
Main Authors: Perry, J, Chanarin, I, Deacon, R, Lumb, M
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC502332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1692039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jcp.43.3.211
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