Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells

We combine a genome-scale RNAi screen in mouse epiblast stem cells (EpiSCs) with genetic interaction, protein localization, and “protein-level dependency” studies—a systematic technique that uncovers post-transcriptional regulation—to delineate the network of factors that control the expression of O...

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Udgivet i:Cell Syst
Main Authors: Ding, Li, Paszkowski-Rogacz, Maciej, Winzi, Maria, Chakraborty, Debojyoti, Theis, Mirko, Singh, Sukhdeep, Ciotta, Giovanni, Poser, Ina, Roguev, Assen, Chu, Wai Kit, Choudhary, Chunaram, Mann, Matthias, Stewart, A. Francis, Krogan, Nevan, Buchholz, Frank
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023010/
https://ncbi.nlm.nih.gov/pubmed/27135800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2015.08.002
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