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Network topology and functional connectivity disturbances precede the onset of Huntington’s disease

Cognitive, motor and psychiatric changes in prodromal Huntington’s disease have nurtured the emergent need for early interventions. Preventive clinical trials for Huntington’s disease, however, are limited by a shortage of suitable measures that could serve as surrogate outcomes. Measures of intrins...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Harrington, Deborah L., Rubinov, Mikail, Durgerian, Sally, Mourany, Lyla, Reece, Christine, Koenig, Katherine, Bullmore, Ed, Long, Jeffrey D., Paulsen, Jane S., Rao, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022662/
https://ncbi.nlm.nih.gov/pubmed/26059655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv145
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