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Synthesis and evaluation of LOX inhibitory activity of 2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-phenylacetamide derivatives

A family of structurally related LOX enzymes present in human cells which catalyse the metabolism of released arachidonic acid from phospholipids by inflammatory stimuli, to biologically active mediators. Mainly, expression of three types of LOXs occurs in cells, which catalyse the insertion of mole...

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Foilsithe in:Res Pharm Sci
Main Authors: Mohammadi-Farani, Ahmad, Haqiqi, Arash, Navid, Sahar Jamshidy, Aliabadi, Alireza
Formáid: Artigo
Teanga:Inglês
Foilsithe: Medknow Publications & Media Pvt Ltd 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022374/
https://ncbi.nlm.nih.gov/pubmed/27651806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.189283
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