Translocation of PKG1α acts on TRPV4-C1 heteromeric channels to inhibit endothelial Ca(2+) entry

AIM: TRPV4-C1 heteromeric channels contribute to store-operated Ca(2+) entry in vascular endothelial cells. However, the negative regulation of these channels is not fully understood. This study was conducted to investigate the inhibitory effect of PKG1α on TRPV4-C1 heteromeric channels. METHODS: Im...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Zhang, Peng, Mao, Ai-qin, Sun, Chun-yuan, Zhang, Xiao-dong, Pan, Qiong-xi, Yang, Dan-tong, Jin, Jian, Tang, Chun-lei, Yang, Zhen-yu, Yao, Xiao-qiang, Lu, Xiao-jie, Ma, Xin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022095/
https://ncbi.nlm.nih.gov/pubmed/27397542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.43
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