Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression

Elevation of the proinflammatory cytokine IL-6 has been implicated in depression; however, the mechanisms remain elusive. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit gene expression post-transcriptionally. The lethal-7 (let-7) miRNA family was suggested to be involved in the inflammati...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Wei, Y B, Liu, J J, Villaescusa, J C, Åberg, E, Brené, S, Wegener, G, Mathé, A A, Lavebratt, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022082/
https://ncbi.nlm.nih.gov/pubmed/27529677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.136
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