An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation

Emerging evidence suggests that inflammation has a key role in depression and suicidal behavior. The kynurenine pathway is involved in neuroinflammation and regulates glutamate neurotransmission. In the cerebrospinal fluid (CSF) of suicidal patients, levels of inflammatory cytokines and the kynureni...

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Publicat a:Transl Psychiatry
Autors principals: Brundin, L, Sellgren, C M, Lim, C K, Grit, J, Pålsson, E, Landén, M, Samuelsson, M, Lundgren, K, Brundin, P, Fuchs, D, Postolache, T T, Traskman-Bendz, L, Guillemin, G J, Erhardt, S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022080/
https://ncbi.nlm.nih.gov/pubmed/27483383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.133
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