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Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage

Characterising and predicting the effects of ionising radiation on cells remains challenging, with the lack of robust models of the underlying mechanism of radiation responses providing a significant limitation to the development of personalised radiotherapy. In this paper we present a mechanistic m...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: McMahon, Stephen J., Schuemann, Jan, Paganetti, Harald, Prise, Kevin M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022028/
https://ncbi.nlm.nih.gov/pubmed/27624453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33290
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