Diosgenin and 5-Methoxypsoralen Ameliorate Insulin Resistance through ER-α/PI3K/Akt-Signaling Pathways in HepG2 Cells

To determine the effects and the underlying mechanism of diosgenin (DSG) and 5-methoxypsoralen (5-MOP), two main active components in the classical Chinese prescription Hu-Lu-Ba-Wan (HLBW), on insulin resistance, HepG2 cells were incubated in medium containing insulin. Treatments with DSG, 5-MOP, an...

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Publicat a:Evid Based Complement Alternat Med
Autors principals: Fang, Ke, Dong, Hui, Jiang, Shujun, Li, Fen, Wang, Dingkun, Yang, Desen, Gong, Jing, Huang, Wenya, Lu, Fuer
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021865/
https://ncbi.nlm.nih.gov/pubmed/27656241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7493694
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